Antiproliferative Effect of Flavonoids from the Halophyte Vitex Rotundifolia on Human Cancer Cells
نویسندگان
چکیده
منابع مشابه
Antiproliferative Effect of Extracts , Fractions and Compound from Vitex rotundifolia on Human Cancer Cells
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15 صفحه اولPhenolic compounds and flavonoids as plant growth regulators from fruit and leaf of Vitex rotundifolia.
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Three new diterpenes (7, 15 and 17) and two new neolignans (19 and 20) along with nineteen known compounds have been isolated from the fruits of Vitex rotundifolia. Their structures were elucidated by a combination of 1D and 2D NMR, HRESI-MS, and CD data. All isolates were tested for their inhibitory activities on LPS-induced nitric oxide production in RAW264.7 cells. Of these, compounds 3, 4, ...
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In the course of screening for antioxidant compounds by measuring the radical scavenging effect on DPPH (1,1-diphenyl2-picrylhydrazyl), a total extract of the twigs of Vitex rotundifolia (Verbenaceae) was found to show potent antioxidant activity. Subsequent activity-guided fractionation of the methanolic extract led to the isolation of three iridoid compounds, 10-O-vanilloylaucubin (1), 10-O-p...
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ژورنال
عنوان ژورنال: Natural Product Communications
سال: 2013
ISSN: 1934-578X,1555-9475
DOI: 10.1177/1934578x1300801016